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    Chemopreventive effects of dietary phytochemicals against cancer invasion-翁家瑞.pdf
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    Chemopreventive effects of dietary phytochemicals against cancer invasion-翁家瑞.pdf檔名:1426002657312.pdf
    篇名/題名:Chemopreventive effects of dietary phytochemicals against cancer invasion and metastasis: Phenolic acids, monophenol, polyphenol, and their derivatives
    摘要:Cancer metastasis is the major cause of cancer-related death, and chemoprevention is defined as the use of natural or synthetic substances to prevent cancer formation or cancer progress. Evidence that phenolic
    compounds may have a potential inhibitory effect on cancer invasion and metastasis is increasingly being reported in the scientific literature. Curcumin, resveratrol, and their related derivatives are the most studied compounds in this topic so far; gallic acid, chlorogenic acid, caffeic acid, carnosol, capsaicin, 6-shogaol, 6-gingerol, and their corresponding derivatives are also suggested to be the active members of the phenolic family on anti-invasion and anti-metastasis. Because metastasis occurs through a multistep
    process, these bioactives might act on a variety of stages of the metastatic process to prevent tumor cells from metastasizing. This review summarizes the common protein targets and signaling pathways for the inhibition of invasion and metastasis as well as past publications on the in vitro and in vivo effects and molecular mechanisms of phenolic acids, monophenol, polyphenol, and their derivatives, except flavonoids, on cancer invasion and metastasis. Based on these data, we conclude that the daily consumption of natural dietary components that are rich in phenolics could be beneficial for the prevention of cancer
    metastasis.
    類型:期刊論文
    西元出版年:2012
    著作語言:en_US
    關鍵詞:PolyphenolMonophenolPhenolic acidsChemopreventionInvasionMetastasis
    作者:翁家瑞、Chia-Jui Weng、Gow-Chin Yen
    學校系所:生活應用科學碩士班